From The Stage

Plaque Reduction Neutralization Tests (PRNT) and the Development of New Antiviral Drugs

Posted by BioAgilytix / / Uncategorized

While infectious disease has always been an important area of scientific and medical research, the recent pandemic has brought this discipline more clearly into the public eye. Understanding which infectious agents are currently of concern to global health and which will become a threat in the future is a complicated and serious undertaking within the scientific community. Infectious agents are a diverse group consisting of bacteria, viruses, parasites, and less common types such as prions. Each of these pathogens represents unique immunological or physiological mechanisms which must be considered when…

What Parameters Are Acquired from a PK Study?

Posted by BioAgilytix / / Uncategorized

The term “Pharmacokinetics” is derived from “pharmakon” and “kinetikos” in ancient Greek, meaning “drug” and “position in motion,” respectively. It is one of the principal assessments in the drug development process that describes what the body does to an administered drug substance and is essential data for defining safe and effective levels of drug to be administered.Currently, in drug development, there is a large variety of drug moieties with variable structures and pharmacological actions. Examples include small molecules, recombinant human proteins, fusion proteins, synthetic peptides, oligonucleotides, monoclonal antibodies, bi- and…

The Broad Array of Vaccine Options for COVID-19

Posted by BioAgilytix / / Viruses

As we pass the two-year anniversary of the start of the coronavirus pandemic, we are reminded of where we started and how far we have come. From day one, we have been able to witness scientific advancements on the world stage as the scientific community quickly came together to address this international health crisis. Through these incredible, coordinated efforts by scientists and companies across the globe, we now have a range of tools with which to combat COVID-19, including multiple vaccines which have been shown to reduce the severity and…

Validation of qPCR Assays for Gene Therapy

Posted by BioAgilytix / / Uncategorized

Though the modern world has progressed a lot in terms of medical interventions and biomedicine, there still are a vast number of diseases and disorders that demand a rather unconventional approach to treatment. Gene therapy has evolved as a technique that aims to address some of these diseases by introducing into a patient a normal copy of one or more defective genes responsible for the patient’s disease. By repairing the damaged gene responsible for the disease, gene therapy aims to introduce a normal copy of the gene into cells containing…