Explore Our Biomarker Menu

Biomarker:

Complement Component 4

Biological or Clinical Significance:

Complement component 4 (C4) is a protein involved in the complement system in human, primate, and other animals. It serves a number of critical functions in the complement system, including contributing component C4B, which bears a reactive thionolactone ring which covalently modifies the cell surfaces of infecting pathogens, and which is a part of the C3 convertase which readies the C3 protein for its role in the complement system. C4 defines the Chido/Rodgers blood group system, and it, and the gene encoding it, are being investigated for its possible role in schizophrenia risk and development.

Complement component 4 is responsible for the Chido/Rodgers blood group system. C4d may be a biomarker for systemic lupus erythematosus. The gene that codes for C4 is being investigated for the role it may play in schizophrenia risk and development.

References:

Analyte:

Complement Component 4

Matrix:

Status:

Experienced Running

Sensitivity-LLOQ:

Sensitivity-ULOQ:

platform

ELISA

Required Sample Volume

Disease State:

MSD Panel:

Speak To A Scientist





    I consent to receive communications (which may include, phone, email, social, and re-targeting ads) from BioAgilytix. I understand I may proactively manage my preferences or opt-out of communications with BioAgilytix at any time using the unsubscribe link provided in all of BioAgilytix’s email communications and can learn more by reading the privacy policy.


    Immunogenicity

    Learn why BioAgilytix is a world-leading authority on immunogenicity studies related to ADA, NAb assay development and validation, isotyping, and more.

    Case Studies

    Learn why we’re a trusted partner to 22 of the top 25 global pharma and biotech companies.