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Biomarker:

Cytokeratin 18

Biological or Clinical Significance:

KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. 

References:

KRT18 keratin 18 [ Homo sapiens (human) ].” (n.d.): n. pag. The National Center for Biotechnology Information (NCBI). Web. 

Analyte:

Cytokeratin 18

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

141 pg/mL

Sensitivity-ULOQ:

platform

Ella

Required Sample Volume

Disease State:

MSD Panel:

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