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Biological or Clinical Significance:

This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

References:

  • “DKK1.” (n.d.): n. pag. The Human Protein Atlas. Web.  

Analyte:

DKK-1

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

20.7 pg/mL

Sensitivity-ULOQ:

platform

Ella

Required Sample Volume

Disease State:

MSD Panel:

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