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Biological or Clinical Significance:

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. 

References:

  • “FAP.” (n.d.): n. pag. The Human Protein Atlas. Web.  

Analyte:

FAP

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

10.5 pg/mL

Sensitivity-ULOQ:

platform

Ella

Required Sample Volume

Disease State:

MSD Panel:

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