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Biomarker: Ferritin

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Analyte:

Ferritin

Platform:

Matrix:

Human Serum

Disease State:

Status:

Validated

Required Sample Volume:

20 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 5.19 ng/mL
ULOQ: 753 ng/mL

Biological or Clinical Significance:

Ferritin is an ubiquitous intracellular protein that stores iron and releases it in a controlled fashion. The protein is produced by almost all living organisms, including algae, bacteria, higher plants, and animals. In humans, it acts as a buffer against iron deficiency and iron overload. Ferritin is found in most tissues as a cytosolic protein, but small amounts are secreted into the serum where it functions as an iron carrier.

References:

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