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Biomarker:

FGF (basic, serum)

Biological or Clinical Significance:

One of the most important functions of fibroblast growth factor-2 (FGF-2 or bFGF) is the promotion of endothelial cell proliferation and the physical organization of endothelial cells into tube-like structures, thus promoting angiogenesis. FGF-2 is a more potent angiogenic factor than VEGF or PDGF (platelet-derived growth factor); however, it is less potent than FGF-1. FGF2 has been used to induce artificial gyrification of the mouse brain. Adult neurogenesis within the hippocampus e.g. depends greatly on FGF2.

References:

Analyte:

FGF (basic, serum)

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

9.46 pg/mL

Sensitivity-ULOQ:

6,900 pg/mL

platform

Luminex

Required Sample Volume

100 µL/well

Disease State:

MSD Panel:

Angiogenesis Panel 1 (Human)

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