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Biomarker:

Flt-1 (sVEGFR1)

Biological or Clinical Significance:

Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family and is related to oncogene ROS (MIM 165020). Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. FLT1 has been shown to interact with PLCG1 and vascular endothelial growth factor B (VEGF-B).

References:

Analyte:

Flt-1 (sVEGFR1)

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

610 pg/mL

Sensitivity-ULOQ:

2,500,000 pg/mL

platform

Luminex

Required Sample Volume

50 µL/well

Disease State:

MSD Panel:

Angiogenesis Panel 1 (Human)

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