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Biomarker: G-CSF

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Analyte:

G-CSF

Platform:

Matrix:

Human Serum

Status:

Experienced Running

Required Sample Volume:

100 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 145 pg/mL
ULOQ: 105,400 pg/mL

Biological or Clinical Significance:

Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. G-CSF is produced by endothelium, macrophages, and a number of other immune cells. The natural human glycoprotein exists in two forms, a 174- and 177-amino-acid-long protein of molecular weight 19,600 grams per mole. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. G-CSF also stimulates the survival, proliferation, differentiation, and function of neutrophil precursors and mature neutrophils.

References:

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