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Biomarker: GFAP

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Analyte:

GFAP

Platform:

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ/ULOQ:

LLOQ: 72.1 pg/mL

Biological or Clinical Significance:

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

References:

  • “GFAP.” (n.d.): n. pag. The Human Protein Atlas. Web.  

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