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Biomarker: HbAI c/Hb

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HbAI c/Hb

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Experienced Running

Biological or Clinical Significance:

Glycated hemoglobin (sometimes also HbA1c or HGBA1C) is a form of hemoglobin that is measured primarily to identify the three month average plasma glucose concentration. It is formed in a non-enzymatic glycation pathway by hemoglobin’s exposure to plasma glucose. Normal levels of glucose produce a normal amount of glycated hemoglobin. As the average amount of plasma glucose increases, the fraction of glycated hemoglobin increases in a predictable way. This serves as a marker for average blood glucose levels over the previous three months before the measurement as this is the lifespan of red blood cells. Glycated hemoglobin testing is recommended for both checking the blood sugar control in people who might be pre-diabetic and monitoring blood sugar control in patients with more elevated levels, termed diabetes mellitus. HbA1c levels are reflective of how well diabetes is controlled.

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