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Biological or Clinical Significance:

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

References:

  • WFDC2.” (n.d.): n. pag. The Human Protein Atlas. Web.  

Analyte:

HE4

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

12.1 pg/mL

Sensitivity-ULOQ:

platform

Ella

Required Sample Volume

Disease State:

MSD Panel:

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