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Biomarker: IFN-gamma

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Analyte:

IFN-gamma

Platform:

Matrix:

Human Serum

Disease State:

null

Status:

Offered

Required Sample Volume:

null

Sensitivity-LLOQ/ULOQ:

LLOQ: 0.99 pg/mL

Biological or Clinical Significance:

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. 

References:

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