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Biomarker: IL-8 HA (plasma)

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Analyte:

IL-8 HA (plasma)

Platform:

Matrix:

Human K2 EDTA Plasma

Disease State:

Status:

Validated

Required Sample Volume:

50 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 2,308 pg/mL
ULOQ: 182,400 pg/mL

Biological or Clinical Significance:

The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.

References:

  • CXCL8.” (n.d.): n. pag. The Human Protein Atlas. Web.  

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