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Biomarker:

MIP-α (CCL3) (plasma)

Biological or Clinical Significance:

Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL3 gene. CCL3 is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes through binding to the receptors CCR1, CCR4 and CCR5.

References:

Analyte:

MIP-α (CCL3) (plasma)

Matrix:

Human K2 EDTA Plasma

Status:

Validated

Sensitivity-LLOQ:

8.64 pg/mL

Sensitivity-ULOQ:

2,280 pg/mL

platform

MSD-ECL

Required Sample Volume

50 µL/well

Disease State:

Autoimmune

MSD Panel:

Chemokine Panel 1 (Human)

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