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Biomarker: MIP-β (CCL4) (plasma)

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Analyte:

MIP-β (CCL4) (plasma)

Platform:

Matrix:

Human K2 EDTA Plasma

Disease State:

Status:

Validated

Required Sample Volume:

50 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 2.936 pg/mL
ULOQ: 2,320 pg/mL

Biological or Clinical Significance:

Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in humans is encoded by the CCL4 gene. CCL4, also known as Macrophage inflammatory protein-1β (MIP-1β) is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. CCL4 has been shown to interact with CCL3.

References:

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