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Biomarker:

Reactive Oxygen

Biological or Clinical Significance:

Reactive oxygen species (ROS) are chemically reactive molecules containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, and singlet oxygen. In a biological context, ROS are formed as a natural byproduct of the normal metabolism of oxygen and have important roles in cell signaling and homeostasis. However, during times of environmental stress, ROS levels can increase dramatically. This may result in significant damage to cell structures. Cumulatively, this is known as oxidative stress. ROS are also generated by exogenous sources such as ionizing radiation.

References:

Analyte:

Reactive Oxygen

Matrix:

0.1M sodium phosphate buffer or water

Status:

Experienced Running

Sensitivity-LLOQ:

200pM

Sensitivity-ULOQ:

1M

platform

Plate-Based Luminescence

Required Sample Volume

5ml

Disease State:

MSD Panel:

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