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Biomarker: sAPPα

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Analyte:

sAPPα

Platform:

Status:

Experienced Running

Biological or Clinical Significance:

sAPPα levels could shift proliferating cells towards tumorigenesis. In contrast to its neuroprotective effects, sAPPα is also able to activate microglia, leading to neurotoxicity. Understanding the mechanisms that underlie the different properties of sAPPα could therefore lead to the development of therapeutic strategies against Alzheimer’s disease, which could be curative as well as preventive.

References:

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