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Biomarker: XBP-1 (total)

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XBP-1 (total)

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Experienced Running

Biological or Clinical Significance:

XBP1 (X-Box Binding Protein 1) is a Protein Coding gene. Diseases associated with XBP1 include major affective disorder-7 and metaphyseal chondrodysplasia, schmid type. Among its related pathways are Transport to the Golgi and subsequent modification and Translational Control. XBP1 functions as a transcription factor during endoplasmic reticulum (ER) stress by regulating the unfolded protein response (UPR). It is required for cardiac myogenesis and hepatogenesis during embryonic development, and the development of secretory tissues such as exocrine pancreas and salivary gland.

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