From The Stage

Large Molecule Sample Analysis for a Large Number of Samples: Why Veteran Expertise is Critical to Success

Dr. Afshin Safavi
Posted by Dr. Afshin Safavi / / CRO Selection, Sample Analysis

When it comes to analyzing large numbers of samples, it is a common misconception that the quality of instrumentation and facility are enough to ensure accurate, consistent results. This may be true for analysis of small molecule drugs, which have simple, stable, well-defined structures and little ability to initiate immune responses. However, the characteristics of large molecule drugs are very different, with numerous intricacies that can impact bioanalytical results. Consider the disparity in levels of complexity alone: aspirin, a typical small molecule drug, has 21 atoms; whereas a large molecule…