The cell-based assay has become a mainstay of drug development, addressing new concerns raised by the advent of biologics. These concerns include the difficulties inherent in characterizing drug efficacy and patient safety in the context of immunogenicity. Whereas small molecule drugs may escape detection by the immune system, larger protein therapeutics, such as monoclonal antibodies, are apt to trigger alarms.

[EPISODE 20] Dr. David Johnson Talks Frosted Flakes, Small Molecules, and Pharmacokinetics!
On this episode of Molecular Moments, Dr. Jim McNally chats with DMPK Senior Director Dr. David Johnson, Ph.D., from BioAgilytix