Scientific Posters

A Quantitative Method for Determining Hyaluronan Content in Plasma by LC/MS/MS and Plasma HA as a PharmacodynamicMarker for PEGylated-Hyaluronidase PH20 (PEGPH20) in a Phase 1b Trial for Pancreatic Ductal Adenocarcinoma

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Hyaluronan (HA) is a non-sulfated linear glycosaminoglycan comprised of repeating disaccharide units of n acetylglucosamineand glucuronic acid.

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Evaluation of the MSD Multiplex Electrochemiluminescent Immunoassy for the Determination of Cardiac Toxicity Biomarkers in Rat Serum

Published by BioAgilytixIntroductionICH guidelines require that preclinical safety pharmacology studies to assess the risk of cardiotoxicity be conducted before beginning any clinical development program. Investigation…

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Evaluation of Multiplex Electrochemiluminescent Immunoassays for Quantitative Determination of Kidney Injury Biomarkers in Rat Urine

Published by BioAgilytixIntroduction Traditional clinical markers of kidney injury, such as BUN and serum creatinine, lack sufficient sensitivity for early detection of injury and are…

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