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Drug	Species	Matrix	Technique	Anticoagulant	Extraction Volume	Range	Stable Labeled I.S.
2-Deoxy-D-Glucose	Human	Plasma	LC/MS	Heparin	0.1 mL	0.25-50 µg/mL	Yes
2-Deoxy-D-Glucose	Human	Urine	LC/MS	N/A	0.1 mL	1-200 µg/mL	Yes
4-Hydroxy Tolbutamide	Human	Plasma	LC/MS	EDTA	0.02 mL	10.0 - 5,000 ng/mL	Yes
5-Amino Salicylic acid N-Acetyl-5-ASA	Rabbit	Plasma	HPLC/UV	Sodium Citrate	0.1 mL	50-5,000 ng/mL	No
5-Amino Salicylic acid N-Acetyl-5-ASA	Dog	Plasma	HPLC/UV	Sodium Citrate	0.1 mL	50-5,000 ng/mL	No
5-Amino Salicylic acid N-Acetyl-5-ASA	Rabbit	Plasma	LC/MS	EDTA	0.025 mL	25-10,000 ng/mL 50-20,000 ng/mL	Yes
5-Amino Salicylic acid N-Acetyl-5-ASA	Dog	Plasma	LC/MS	EDTA	0.025 mL	50-25,000 ng/mL 25-12,500 ng/mL	Yes
5-Fluorouracil	Human	Plasma	LC/MS	Heparin	0.05 mL	5-2,500 ng/mL	Yes
5-Methyltetrahydrofolate (6R/6S)	Human	Plasma	LC/MS	Heparin	0.1 mL	10.0 - 10,000 ng/mL	Yes
17-alpha Hydroxypregnenolone	Rat/Dog	Plasma	LC/MS	EDTA	0.05 mL	0.100 - 50.0 ng/mL	Yes
17-alpha Hydroxyprogesterone	Rat/Dog	Plasma	LC/MS	EDTA	0.05 mL	0.0500 - 25.0 ng/mL	Yes
25-Desacetyl Rifaximin	Human	Plasma	LC/MS	Heparin	0.05 mL	0.100 - 25.0 ng/mL	Yes
Acetaminophen	Human	Plasma	HPLC/UV	Heparin	0.1 mL	0.5-50 µg/mL	No
Adapalene	Human	Plasma	LC/FLD	EDTA	0.1 mL	0.250 - 25.0 ng/mL	No
Allopurinol	Human	Serum	LC/MS	N/A	0.025 mL	0.0500 - 10 ug/mL	Yes
Alogliptin	Human	Plasma	LC/MS	EDTA	0.2 mL	0.500 - 200 ng/mL	Yes
Alprazolam α-OH-Alprazolam 4-OH-Alprazolam	Human	Plasma	LC/MS	EDTA	0.050 mL	0.100-100 ng/mL	Yes
Amitriptyline Nortriptyline	Human	Plasma	LC/MS	Heparin	0.1 mL	0.25-250 ng/mL	Yes
Anandamide	Human	Plasma	LC/MS	Heparin	0.1 mL	0.1-5 ng/mL	Yes
Anastrozole	Human	Plasma	LC/MS	Heparin	0.1 mL	1-100 ng/mL	Yes
Aplindore	Human	Plasma	LC/MS	Heparin	0.5 mL	10-5,000 pg/mL	Yes
Atorvastatin p-hydroxyatorvastatin o-hydroxyatrovastatin	Human	Plasma	LC/MS	EDTA or Heparin	0.05 mL	0.1-20 ng/mL	Yes
BDNF	Human	Serum	ELISA	N/A	0.02 mL	0.350 - 4.80 ng/mL	N/A
Benzoic acid	Minipig	Plasma	HPLC/UV	EDTA	0.1 mL	50-2,000 ng/mL	No
Benzoylecgonine	Human	Plasma	LC/MS	Heparin	0.2 mL	25-10,000 ng/mL	Yes
Benzyl alcohol	Human	Plasma	HPLC/UV	EDTA	0.1 mL	1-100 µg/mL	No
Besifloxacin	Human	Plasma	LC/MS	EDTA	0.05 mL	0.0500 - 50.0 ng/mL	Yes
Bromfenac	Human	Serum	HPLC/UV	N/A	0.25 mL	50-10,000 ng/mL	No
Budesonide	Human	Plasma	LC/MS	EDTA	0.4 mL	10.0 - 2,000 pg/mL	Yes
Caffeine 1,7-dimethylxanthine	Human	Plasma	LC/MS	Heparin	0.1 mL	100-50,000 ng/mL 50-25,000 ng/mL	No
Caffeine 1,7-dimethylxanthine	Human	Urine	LC/MS	N/A	0.1 mL	500-25,000 ng/mL	No
Calcipotriene	Human	Plasma	LC/MS	Heparin	1.0 mL	10-2,000 pg/mL	No
cAMP	Human	Plasma	LC/MS	EDTA	0.025 mL	2.00 - 200 ng/mL	No
Campesterol ß-Sitosterol Campestanol Sitostanol	Human	Plasma	LC/MS	EDTA	0.1 mL	1,000-8,800 ng/mL 1,000-13,400 ng/mL 4-1,000 ng/mL 5-1,700 ng/mL	Yes
Carbamazepine	Human	Plasma	LC/MS	Citrate	0.08 mL	5.00 - 1,000 ng/mL	Yes
Carboxyethylphosphoramide mustard (CEPM)	Human	Plasma	LC/MS	Heparin	0.05 mL	0.05-50 µg/mL	Yes
Cephalothin	Rat	Plasma	HPLC/UV	Heparin	0.1 mL	0.5-50 µg/mL	No
Cetylpyridinium	Human	Plasma	LC/MS	Heparin	0.1 mL	1-200 ng/mL	Yes
cGMP	Human	Plasma	LC/MS	EDTA	0.05 mL	1.00 - 1,000 ng/mL	Yes
cGMP	Human	Urine	LC/MS	N/A	0.02 mL	5.00 - 5,000 ng/mL	Yes
cGMP	Human	CSF	LC/MS	N/A	0.2 mL	0.100 - 20.0 ng/mL	Yes
Chloroadenine	Human	Plasma	LC/MS	Heparin	0.1 mL	1-500 ng/mL	No
Cimetidine	Human	Plasma	LC/MS	EDTA or Heparin	0.05 mL	5-5,000 ng/mL	Yes
Ciprofloxacin	Human	Plasma	LC/MS	EDTA	0.2 mL	1.87 - 935 ng/mL	Yes
Cisplatin	Human	Plasma	LC/MS	Heparin	0.05 mL	20.0 - 5,000 ng/mL	No
Citrulline	Rat	Plasma	LC/MS	Heparin	0.1 mL	2-200 µg/mL	No
Clindamycin Clindamycin sulfoxide	Human	Plasma	LC/MS	EDTA	0.05 mL	50-20,000 pg/mL	No
Clobetasol propionate	Human	Plasma	LC/MS	EDTA	0.4 mL	20-10,000 pg/mL	No
Clofarabine	Human	Plasma	LC/MS	Heparin	0.2 mL	0.100 - 50.0 ng/mL	No
Clozapine	Human	Plasma	LC/MS	Heparin	0.05 mL	0.2-200 ng/mL	Yes
Cocaine Norcocaine Cocaethylene	Human	Plasma	LC/MS	Heparin	0.2 mL	25-10,000 ng/mL	Yes
Cordycepin	Human	Whole Blood	LC/MS	EDTA	0.05 mL	0.1-10 µg/mL	Yes
Cortisol	Rat/Dog	Plasma	LC/MS	EDTA	0.05 mL	1.00 - 500 ng/mL	Yes
Cortisol 6ß-hydroxycortisol	Human	Urine	LC/MS	N/A	1.0 mL	5-250 ng/mL 50-2,500 ng/mL	No
Cytarabine	Human	Plasma	LC/MS	EDTA	0.05 mL	2-500 ng/mL	Yes
Daunorubicin Daunorubicinol	Human	Plasma	LC/MS	EDTA	0.1 mL	1-1,000 ng/mL 0.2-200 ng/mL	Yes
Dehydroepiandrosterone	Rat/Dog	Plasma	LC/MS	EDTA	0.05 mL	0.100 - 50.0 ng/mL	Yes
Diclofenac	Human	Plasma	LC/MS	Heparin	0.1 mL	1-1,000 ng/mL	Yes
Digoxin	Human	Plasma	LC/MS	Heparin	0.2 mL	0.1-10 ng/mL	Yes
Docetaxel	Human	Plasma	LC/MS	Heparin	0.25 mL	0.5-100 ng/mL	Yes
Dopamine	Human	Plasma	LC/MS	EDTA	0.2 mL	2.00 - 400 pg/mL	Yes
Dopamine	Human	CSF	LC/MS	N/A	0.2 mL	2.00 - 400 pg/mL	Yes
Doxycycline	Human	Plasma	LC/MS	Heparin	0.05 mL	10.0 - 4,000 ng/mL	No
Econazole	Human	Plasma	HPLC/UV	Heparin	1.0 mL	20-1,000 ng/mL 20-1,000 ng/mL	No
Econazole	Human	Plasma	LC/MS	EDTA	0.2 mL	100-50,000 pg/mL	No
Erlotinib	Human	Plasma	LC/MS	Heparin	0.025 mL	10-10,000 ng/mL	Yes
Ethinyl estradiol	Human	Plasma	LC/MS	Heparin	0.5 mL	2-500 pg/mL	Yes
Etoposide	Human	Plasma	LC/MS	Heparin	0.02 mL	0.100-100 µg/mL	Yes
Fentanyl	Human	Plasma	LC/MS	Heparin	0.1 mL	50-20,000 pg/mL	No
Finasteride	Human	Plasma	LC/MS	EDTA	0.025 mL	20.0 - 50,000 ng/mL	Yes
Fludarabine desphosphate	Human	Plasma	LC/MS	Heparin	0.1 mL	0.5-500 ng/mL	No
Fluticasone Propionate	Human	Plasma	LC/MS	EDTA	1.0 mL	0.250 - 50.0 pg/mL	Yes
Ganaxolone	Human	Plasma	LC/MS	EDTA	0.2 mL	5-1,500 ng/mL	No
Gefitinib	Human	Plasma	LC/MS	Heparin	0.05 mL	5-1,000 ng/mL	Yes
Gemcitabine	Human	Plasma	LC/MS	Heparin	0.05 mL	10-10,000 ng/mL	Yes
Gemfibrozil	Human	Plasma	LC/MS	Heparin	0.025 mL	0.1-500 µg/mL	Yes
Gentamicin	Human	Plasma	LC/MS	Heparin	0.05 mL	2-5,000 ng/mL	Yes
Glimepiride	Human	Plasma	LC/MS	Heparin	0.05 mL	2-2,000 ng/mL	Yes
Glyburide	Human	Plasma	LC/MS	EDTA or Heparin	0.1 mL	1-500 ng/mL	No
Herceptin	Human	Plasma	MSD	K3EDTA	0.025 mL	0.137-100 µg/mL	No
Histamine N-methylhistamine	Human	Plasma	LC/MS	EDTA	0.5 mL	0.2-50 ng/mL	Yes
Histamine N-methylhistamine	Human	Urine	LC/MS	N/A	0.05 mL	10-2,000 ng/mL 50-10,000 ng/mL	Yes
Hydroxy Itraconazole	Human	Plasma	LC/MS	Heparin	0.05 mL	20.0 - 2,000 ng/mL	Yes
Hydroxy Pioglitazone (M-IV)	Human	Plasma	LC/MS	EDTA	0.05 mL	0.500 - 500 ng/mL	Yes
Indomethacin	Human	Plasma	LC/MS	EDTA	0.02 mL	20-4,000 ng/mL	Yes
Itraconazole	Human	Plasma	LC/MS	Heparin	0.05 mL	20.0 - 2,000 ng/mL	Yes
Ketoconazole	Human	Plasma	LC/MS	EDTA	0.05 mL	5-5,000 ng/mL	Yes
Lamotrigine	Human	Plasma	LC/MS	Heparin	0.025 mL	0.025-25 µg/mL	Yes
L-Arginine	Human	Plasma	HPLC/UV	Heparin	0.125 mL	1-250 µg/mL	No
Leucovorin (6R/6S)	Human	Plasma	LC/MS	Heparin	0.1 mL	10.0 - 10,000 ng/mL	Yes
Levetiracetam	Human	Plasma	LC/MS	EDTA	0.1 mL	100 - 50,000 ng/mL	Yes
Levofloxacin	Human	Plasma	LC/MS	Heparin	0.025 mL	10-10,000 ng/mL	Yes
Lidocaine	Human	Plasma	LC/MS	Heparin	0.1 mL	0.2-100 ng/mL	No
Lidocaine	Human	Plasma	LC/MS	EDTA	0.1 mL	0.2-100 ng/mL	Yes
Lidocaine 2,6 - dimethylaniline Monoethylglycinexylidide Glycinexylidide	Human	Plasma	LC/MS	EDTA or Heparin	0.1 mL	0.2-200 ng/mL 1-1,000 ng/mL	Yes
L-Methionine	Human	Plasma	LC/MS	Heparin	0.1 mL	1-200 µg/mL	Yes
Lucanthone Hycanthone	Human	Plasma	LC/MS	Heparin	0.05 mL	1-200 ng/mL	Yes
Metformin	Human	Plasma	LC/MS	Heparin	0.05 mL	10-2,000 ng/mL	Yes
Methotrexate	Human	Plasma	LC/MS	Heparin	0.05 mL	1-1,000 ng/mL	Yes
Metoprolol	Human	Plasma	LC/MS	EDTA	0.05 mL	1.00 - 500 ng/mL	Yes
Midazolam	Human	Plasma	LC/MS	EDTA	0.1 mL	0.5-250 ng/mL	No
Midazolam 1-hydroxymidazolam	Human	Plasma	LC/MS	EDTA	0.1 mL	0.5-100 ng/mL	Yes
Mifepristone	Human	Plasma	LC/MS	Heparin	0.05 mL	10-2,000 ng/mL	Yes
Mifepristone	Human	Plasma	LC/MS	EDTA or Heparin	0.05 mL	100 - 10,000 ng/mL	Yes
Minocycline	Human	Plasma	LC/MS	Heparin	0.05 mL	10.0 - 4,000 ng/mL	Yes
Minocycline	Human	Plasma	LC/MS	Heparin	0.05 mL	10.0 - 4,000 ng/mL	Yes
Mitiglinide	Human	Plasma	LC/MS	Heparin	0.1 mL	1-1,000 ng/mL	No
Mitomycin	Human	Plasma	LC/MS	EDTA	0.05 mL	10-5,000 ng/mL	No
Morphine Morphine-6-ß-D-glucuronide	Human	Plasma	LC/MS	Heparin	0.1 mL	0.5-500 ng/mL	Yes
Moxifloxacin	Human	Plasma	LC/MS	EDTA	0.025 mL	10.0 - 5,000 ng/mL	Yes
Nabilone	Human	Plasma	LC/MS	Heparin	0.5 mL	100-20,000 pg/mL	No
N-acetylcysteine	Dog	Plasma	LC/MS	EDTA	0.025 mL	1-1,000 µg/mL	Yes
N-acetylcysteine	Rabbit	Plasma	LC/MS	EDTA	0.025 mL	1-1,000 µg/mL	Yes
Nalbuphine	Human	Plasma	LC/MS	Heparin	0.25 mL	0.1-50 ng/mL	No
Naloxone	Human	Plasma	LC/MS	Heparin	0.25 mL	0.1-50 ng/mL	No
Naproxen	Human	Plasma	LC/MS	Heparin	0.025 mL	0.100-100 µg/mL	Yes
Nifuratel	Human	Plasma	LC/MS	Heparin	0.1 mL	1.00 - 200 ng/mL	No
Nintedanib	Human	Plasma	LC/MS	EDTA	0.05 mL	0.0500 - 50.0 ng/mL	Yes
Nitedanib Carboxylic aicd	Human	Plasma	LC/MS	EDTA	0.05 mL	0.0500 - 50.0 ng/mL	Yes
Norethindrone	Human	Plasma	LC/MS	Heparin	0.25 mL	20-10,000 pg/mL	Yes
Norflaxacin	Human	Plasma	LC/MS	EDTA	0.1 mL	10.0 - 1,000 ng/mL	Yes
Norgestrel 17-deacetylnorgestimate	Human	Plasma	LC/MS	Heparin	0.25 mL	40-20,000 pg/mL 20-10,000 pg/mL	Yes
Omeprazole	Human	Plasma	LC/MS	EDTA	0.05 mL	1.00 - 1,000 ng/mL	Yes
Omeprazole sulfone	Human	Plasma	LC/MS	EDTA	0.05 mL	0.500 - 500 ng/mL	Yes
Ondansetron	Human	Plasma	LC/MS	Heparin	0.05 mL	0.5-250 ng/mL	Yes
Oxybutynin	Human	Plasma	LC/MS	Heparin	0.4 mL	0.0500 - 25.0 ng/mL	Yes
Oxycodone	Human	Plasma	LC/MS	EDTA or Heparin	0.1 mL	0.2-50 ng/mL	Yes
Oxycodone Oxymorphone Noroxycodone	Human	Plasma	LC/MS	Heparin	0.5 mL	0.05-25 ng/mL	Yes
Oxypurinol	Human	Serum	LC/MS	N/A	0.025 mL	0.100 - 20.0 ug/mL	Yes
Paclitaxel	Human	Plasma	LC/MS	EDTA or Heparin	0.1 mL	0.5-200 ng/mL	No
Pioglitazone	Human	Plasma	LC/MS	EDTA	0.05 mL	1.00 - 1,000 ng/mL	Yes
Piperacillin	Human	Plasma	LC/MS	Heparin	0.025 mL	0.0500 - 50.0 ug/mL	No
Piperacillin	Human	ELF	LC/MS	N/A	0.8 mL	1.00 - 500 ng/mL	No
Prednisolone	Human	Plasma	LC/MS	Heparin	0.1 mL	1.00 - 1,000 ng/mL	Yes
Prednisone	Human	Plasma	LC/MS	Heparin	0.1 mL	1.00 - 1,000 ng/mL	Yes
Prilocaine	Human	Plasma	LC/MS	EDTA	0.05 mL	0.2-100 ng/mL	No
Promethazine	Human	Plasma	LC/MS	Heparin	0.1 mL	0.2-100 ng/mL	No
Quetiapine	Human	Plasma	LC/MS	EDTA or Heparin	0.05 mL	1-1,000 ng/mL	Yes
Repaglinide	Human	Plasma	LC/MS	EDTA	0.05 mL	0.1-100 ng/mL	Yes
Repaglinide	Human	Plasma	LC/MS	EDTA	0.05 mL	0.100 - 100 ng/mL	Yes
Repaglinide	Human	Plasma	LC/MS	Heparin	0.2 mL	0.100 - 100 ng/mL	Yes
Ribavirin	Human	Plasma	LC/MS	Heparin	0.05 mL	5.00 - 2,500 ng/mL	Yes
Riboflavin Riboflavin 5-phosphate	Dog	Plasma	Fluorescence	Heparin	0.05 mL	20-10,000 ng/mL 40-20,000 ng/mL	No
Riboflavin Riboflavin 5-phosphate	Rat	Plasma	Fluorescence	Heparin	0.05 mL	20-10,000 ng/mL 40-20,000 ng/mL	No
Rifampin 25-desacetylrifampin	Human	Plasma	LC/MS	EDTA	0.05 mL	0.1-20 µg/mL	Yes
Rifaximin	Human	Plasma	LC/MS	Heparin	0.05 mL	0.100 - 25.0 ng/mL	Yes
Rifaximin	Human	Urine	LC/MS	N/A	0.5 mL	0.200 - 100 ng/mL	Yes
Riluzole	Human	Serum	LC/MS	N/A	0.1 mL	1-500 ng/mL	No
Risperidone 9- hydroxyrisperidone	Human	Plasma	LC/MS	Heparin	0.05 mL	0.1-100 ng/mL	Yes
Ropivacaine	Human	Plasma	LC/MS	Heparin	0.02 mL	1.00 - 1,000 ng/mL	Yes
Rosuvastatin n-desmethyl rosuvastatin	Human	Plasma	LC/MS	Heparin	0.1 mL	0.1-50 ng/mL	Yes
Simvastatin Simvastatin hydroxy acid	Human	Plasma	LC/MS	Heparin	0.25 mL	0.05-50 ng/mL	Yes
Sitagliptin	Human	Plasma	LC/MS	Heparin	0.2 mL	0.500 - 1,000 ng/mL	Yes
Sorafenib	Human	Plasma	LC/MS	EDTA	0.05 mL	10-10,000 ng/mL	Yes
Sumatriptan	Human	Plasma	LC/MS	Heparin	0.1 mL	1-200 ng/mL	No
Tazobactam	Human	Plasma	LC/MS	Heparin	0.02 mL	0.100 - 60.0 ug/mL	No
Tazobactam	Human	ELF	LC/MS	N/A	0.02 mL	1.00 - 250 ng/mL	No
Tazobactam M1	Human	Plasma	LC/MS	Heparin	0.02 mL	0.0500 - 30.0 ug/mL	No
Tenofovir	Human	Plasma	LC/MS	Heparin	0.1 mL	2.00 - 1,000 ng/mL	Yes
Tolbutamide	Human	Plasma	LC/MS	EDTA	0.1 mL	0.1-20 µg/mL	No
Tolbutamide	Human	Plasma	LC/MS	EDTA	0.02 mL	100 - 50,000 ng/mL	Yes
Tolbutamide 4-hydroxytolbutamide	Human	Urine	LC/MS	N/A	0.1 mL	0.1-20 µg/mL	No
Trazodone	Human	Plasma	LC/MS	Heparin	0.05 mL	0.2-200 ng/mL	Yes
Tretinoin	Human	Plasma	LC/MS	EDTA	0.2 mL	0.4-10 ng/mL	Yes
Trimetazidine	Human	Plasma	LC/MS	Heparin	0.2 mL	0.200 - 100 ng/mL	Yes
Urea	Human	Plasma	Colorimetric	EDTA	0.01 mL	2.50 - 50.0 mg/dL	N/A
Urea	Human	ELF	Colorimetric	N/A	0.3 mL	0.0500 - 1.00 mg/dL	N/A
Valerenic acid Hydroxyvalerenic acid Acetoxyvalerenic acid	Human	Plasma	LC/MS	Heparin	0.2 mL	1-500 ng/mL	No
Vancomycin	Human	Plasma	LC/MS	Heparin	0.02 mL	50-25,000 ng/mL	No
Vidagliptin	Human	Plasma	LC/MS	Heparin	0.2 mL	0.500 - 500 ng/mL	Yes
Voruciclib	Human	Plasma	LC/MS	EDTA	0.1 mL	5.00 - 2,000 ng/mL	Yes
Warfarin (R-)	Human	Plasma	LC/MS	Heparin	0.025 mL	2-2,000 ng/mL	Yes
Warfarin (S-)	Human	Plasma	LC/MS	Heparin	0.025 mL	2-2,000 ng/mL	Yes
Yohimbine	Human	Plasma	LC/MS	EDTA	0.1 mL	0.1-50 ng/mL	No
Zolpidem	Human	Plasma	LC/MS	EDTA	0.05 mL	1-150 ng/mL	Yes
Zolpidem	Baboon	Plasma	LC/MS	EDTA	0.05 mL	1-1,000 ng/mL	Yes

Drug

Species

Matrix

Technique

Anticoagulant

Extraction Volume

Range

Stable Labeled I.S.

2-Deoxy-D-Glucose

Human

Plasma

LC/MS

Heparin

0.1 mL

0.25-50 µg/mL

Yes

2-Deoxy-D-Glucose

Human

Urine

LC/MS

N/A

0.1 mL

1-200 µg/mL

Yes

4-Hydroxy Tolbutamide

Human

Plasma

LC/MS

EDTA

0.02 mL

10.0 - 5,000 ng/mL

Yes

5-Amino Salicylic acid
N-Acetyl-5-ASA

Rabbit

Plasma

HPLC/UV

Sodium Citrate

0.1 mL

50-5,000 ng/mL

5-Amino Salicylic acid
N-Acetyl-5-ASA

Dog

Plasma

HPLC/UV

Sodium Citrate

0.1 mL

50-5,000 ng/mL

5-Amino Salicylic acid
N-Acetyl-5-ASA

Rabbit

Plasma

LC/MS

EDTA

0.025 mL

25-10,000 ng/mL
50-20,000 ng/mL

Yes

5-Amino Salicylic acid
N-Acetyl-5-ASA

Dog

Plasma

LC/MS

EDTA

0.025 mL

50-25,000 ng/mL
25-12,500 ng/mL

Yes

5-Fluorouracil

Human

Plasma

LC/MS

Heparin

0.05 mL

5-2,500 ng/mL

Yes

5-Methyltetrahydrofolate (6R/6S)

Human

Plasma

LC/MS

Heparin

0.1 mL

10.0 - 10,000 ng/mL

Yes

17-alpha Hydroxypregnenolone

Rat/Dog

Plasma

LC/MS

EDTA

0.05 mL

0.100 - 50.0 ng/mL

Yes

17-alpha Hydroxyprogesterone

Rat/Dog

Plasma

LC/MS

EDTA

0.05 mL

0.0500 - 25.0 ng/mL

Yes

25-Desacetyl Rifaximin

Human

Plasma

LC/MS

Heparin

0.05 mL

0.100 - 25.0 ng/mL

Yes

Acetaminophen

Human

Plasma

HPLC/UV

Heparin

0.1 mL

0.5-50 µg/mL

Adapalene

Human

Plasma

LC/FLD

EDTA

0.1 mL

0.250 - 25.0 ng/mL

Allopurinol

Human

Serum

LC/MS

N/A

0.025 mL

0.0500 - 10 ug/mL

Yes

Alogliptin

Human

Plasma

LC/MS

EDTA

0.2 mL

0.500 - 200 ng/mL

Yes

Alprazolam
α-OH-Alprazolam
4-OH-Alprazolam

Human

Plasma

LC/MS

EDTA

0.050 mL

0.100-100 ng/mL

Yes

Amitriptyline
Nortriptyline

Human

Plasma

LC/MS

Heparin

0.1 mL

0.25-250 ng/mL

Yes

Anandamide

Human

Plasma

LC/MS

Heparin

0.1 mL

0.1-5 ng/mL

Yes

Anastrozole

Human

Plasma

LC/MS

Heparin

0.1 mL

1-100 ng/mL

Yes

Aplindore

Human

Plasma

LC/MS

Heparin

0.5 mL

10-5,000 pg/mL

Yes

Atorvastatin
p-hydroxyatorvastatin
o-hydroxyatrovastatin

Human

Plasma

LC/MS

EDTA or Heparin

0.05 mL

0.1-20 ng/mL

Yes

BDNF

Human

Serum

ELISA

N/A

0.02 mL

0.350 - 4.80 ng/mL

N/A

Benzoic acid

Minipig

Plasma

HPLC/UV

EDTA

0.1 mL

50-2,000 ng/mL

Benzoylecgonine

Human

Plasma

LC/MS

Heparin

0.2 mL

25-10,000 ng/mL

Yes

Benzyl alcohol

Human

Plasma

HPLC/UV

EDTA

0.1 mL

1-100 µg/mL

Besifloxacin

Human

Plasma

LC/MS

EDTA

0.05 mL

0.0500 - 50.0 ng/mL

Yes

Bromfenac

Human

Serum

HPLC/UV

N/A

0.25 mL

50-10,000 ng/mL

Budesonide

Human

Plasma

LC/MS

EDTA

0.4 mL

10.0 - 2,000 pg/mL

Yes

Caffeine
1,7-dimethylxanthine

Human

Plasma

LC/MS

Heparin

0.1 mL

100-50,000 ng/mL
50-25,000 ng/mL

Caffeine
1,7-dimethylxanthine

Human

Urine

LC/MS

N/A

0.1 mL

500-25,000 ng/mL

Calcipotriene

Human

Plasma

LC/MS

Heparin

1.0 mL

10-2,000 pg/mL

cAMP

Human

Plasma

LC/MS

EDTA

0.025 mL

2.00 - 200 ng/mL

Campesterol
ß-Sitosterol
Campestanol
Sitostanol

Human

Plasma

LC/MS

EDTA

0.1 mL

1,000-8,800 ng/mL
1,000-13,400 ng/mL
4-1,000 ng/mL
5-1,700 ng/mL

Yes

Carbamazepine

Human

Plasma

LC/MS

Citrate

0.08 mL

5.00 - 1,000 ng/mL

Yes

Carboxyethylphosphoramide mustard (CEPM)

Human

Plasma

LC/MS

Heparin

0.05 mL

0.05-50 µg/mL

Yes

Cephalothin

Rat

Plasma

HPLC/UV

Heparin

0.1 mL

0.5-50 µg/mL

Cetylpyridinium

Human

Plasma

LC/MS

Heparin

0.1 mL

1-200 ng/mL

Yes

cGMP

Human

Plasma

LC/MS

EDTA

0.05 mL

1.00 - 1,000 ng/mL

Yes

cGMP

Human

Urine

LC/MS

N/A

0.02 mL

5.00 - 5,000 ng/mL

Yes

cGMP

Human

CSF

LC/MS

N/A

0.2 mL

0.100 - 20.0 ng/mL

Yes

Chloroadenine

Human

Plasma

LC/MS

Heparin

0.1 mL

1-500 ng/mL

Cimetidine

Human

Plasma

LC/MS

EDTA or Heparin

0.05 mL

5-5,000 ng/mL

Yes

Ciprofloxacin

Human

Plasma

LC/MS

EDTA

0.2 mL

1.87 - 935 ng/mL

Yes

Cisplatin

Human

Plasma

LC/MS

Heparin

0.05 mL

20.0 - 5,000 ng/mL

Citrulline

Rat

Plasma

LC/MS

Heparin

0.1 mL

2-200 µg/mL

Clindamycin
Clindamycin sulfoxide

Human

Plasma

LC/MS

EDTA

0.05 mL

50-20,000 pg/mL

Clobetasol propionate

Human

Plasma

LC/MS

EDTA

0.4 mL

20-10,000 pg/mL

Clofarabine

Human

Plasma

LC/MS

Heparin

0.2 mL

0.100 - 50.0 ng/mL

Clozapine

Human

Plasma

LC/MS

Heparin

0.05 mL

0.2-200 ng/mL

Yes

Cocaine
Norcocaine
Cocaethylene

Human

Plasma

LC/MS

Heparin

0.2 mL

25-10,000 ng/mL

Yes

Cordycepin

Human

Whole Blood

LC/MS

EDTA

0.05 mL

0.1-10 µg/mL

Yes

Cortisol

Rat/Dog

Plasma

LC/MS

EDTA

0.05 mL

1.00 - 500 ng/mL

Yes

Cortisol
6ß-hydroxycortisol

Human

Urine

LC/MS

N/A

1.0 mL

5-250 ng/mL
50-2,500 ng/mL

Cytarabine

Human

Plasma

LC/MS

EDTA

0.05 mL

2-500 ng/mL

Yes

Daunorubicin
Daunorubicinol

Human

Plasma

LC/MS

EDTA

0.1 mL

1-1,000 ng/mL
0.2-200 ng/mL

Yes

Dehydroepiandrosterone

Rat/Dog

Plasma

LC/MS

EDTA

0.05 mL

0.100 - 50.0 ng/mL

Yes

Diclofenac

Human

Plasma

LC/MS

Heparin

0.1 mL

1-1,000 ng/mL

Yes

Digoxin

Human

Plasma

LC/MS

Heparin

0.2 mL

0.1-10 ng/mL

Yes

Docetaxel

Human

Plasma

LC/MS

Heparin

0.25 mL

0.5-100 ng/mL

Yes

Dopamine

Human

Plasma

LC/MS

EDTA

0.2 mL

2.00 - 400 pg/mL

Yes

Dopamine

Human

CSF

LC/MS

N/A

0.2 mL

2.00 - 400 pg/mL

Yes

Doxycycline

Human

Plasma

LC/MS

Heparin

0.05 mL

10.0 - 4,000 ng/mL

Econazole

Human

Plasma

HPLC/UV

Heparin

1.0 mL

20-1,000 ng/mL
20-1,000 ng/mL

Econazole

Human

Plasma

LC/MS

EDTA

0.2 mL

100-50,000 pg/mL

Erlotinib

Human

Plasma

LC/MS

Heparin

0.025 mL

10-10,000 ng/mL

Yes

Ethinyl estradiol

Human

Plasma

LC/MS

Heparin

0.5 mL

2-500 pg/mL

Yes

Etoposide

Human

Plasma

LC/MS

Heparin

0.02 mL

0.100-100 µg/mL

Yes

Fentanyl

Human

Plasma

LC/MS

Heparin

0.1 mL

50-20,000 pg/mL

Finasteride

Human

Plasma

LC/MS

EDTA

0.025 mL

20.0 - 50,000 ng/mL

Yes

Fludarabine desphosphate

Human

Plasma

LC/MS

Heparin

0.1 mL

0.5-500 ng/mL

Fluticasone Propionate

Human

Plasma

LC/MS

EDTA

1.0 mL

0.250 - 50.0 pg/mL

Yes

Ganaxolone

Human

Plasma

LC/MS

EDTA

0.2 mL

5-1,500 ng/mL

Gefitinib

Human

Plasma

LC/MS

Heparin

0.05 mL

5-1,000 ng/mL

Yes

Gemcitabine

Human

Plasma

LC/MS

Heparin

0.05 mL

10-10,000 ng/mL

Yes

Gemfibrozil

Human

Plasma

LC/MS

Heparin

0.025 mL

0.1-500 µg/mL

Yes

Gentamicin

Human

Plasma

LC/MS

Heparin

0.05 mL

2-5,000 ng/mL

Yes

Glimepiride

Human

Plasma

LC/MS

Heparin

0.05 mL

2-2,000 ng/mL

Yes

Glyburide

Human

Plasma

LC/MS

EDTA or Heparin

0.1 mL

1-500 ng/mL

Herceptin

Human

Plasma

MSD

K3EDTA

0.025 mL

0.137-100 µg/mL

Histamine
N-methylhistamine

Human

Plasma

LC/MS

EDTA

0.5 mL

0.2-50 ng/mL

Yes

Histamine
N-methylhistamine

Human

Urine

LC/MS

N/A

0.05 mL

10-2,000 ng/mL
50-10,000 ng/mL

Yes

Hydroxy Itraconazole

Human

Plasma

LC/MS

Heparin

0.05 mL

20.0 - 2,000 ng/mL

Yes

Hydroxy Pioglitazone (M-IV)

Human

Plasma

LC/MS

EDTA

0.05 mL

0.500 - 500 ng/mL

Yes

Indomethacin

Human

Plasma

LC/MS

EDTA

0.02 mL

20-4,000 ng/mL

Yes

Itraconazole

Human

Plasma

LC/MS

Heparin

0.05 mL

20.0 - 2,000 ng/mL

Yes

Ketoconazole

Human

Plasma

LC/MS

EDTA

0.05 mL

5-5,000 ng/mL

Yes

Lamotrigine

Human

Plasma

LC/MS

Heparin

0.025 mL

0.025-25 µg/mL

Yes

L-Arginine

Human

Plasma

HPLC/UV

Heparin

0.125 mL

1-250 µg/mL

Leucovorin (6R/6S)

Human

Plasma

LC/MS

Heparin

0.1 mL

10.0 - 10,000 ng/mL

Yes

Levetiracetam

Human

Plasma

LC/MS

EDTA

0.1 mL

100 - 50,000 ng/mL

Yes

Levofloxacin

Human

Plasma

LC/MS

Heparin

0.025 mL

10-10,000 ng/mL

Yes

Lidocaine

Human

Plasma

LC/MS

Heparin

0.1 mL

0.2-100 ng/mL

Lidocaine

Human

Plasma

LC/MS

EDTA

0.1 mL

0.2-100 ng/mL

Yes

Lidocaine
2,6 - dimethylaniline
Monoethylglycinexylidide
Glycinexylidide

Human

Plasma

LC/MS

EDTA or Heparin

0.1 mL

0.2-200 ng/mL
1-1,000 ng/mL

Yes

L-Methionine

Human

Plasma

LC/MS

Heparin

0.1 mL

1-200 µg/mL

Yes

Lucanthone
Hycanthone

Human

Plasma

LC/MS

Heparin

0.05 mL

1-200 ng/mL

Yes

Metformin

Human

Plasma

LC/MS

Heparin

0.05 mL

10-2,000 ng/mL

Yes

Methotrexate

Human

Plasma

LC/MS

Heparin

0.05 mL

1-1,000 ng/mL

Yes

Metoprolol

Human

Plasma

LC/MS

EDTA

0.05 mL

1.00 - 500 ng/mL

Yes

Midazolam

Human

Plasma

LC/MS

EDTA

0.1 mL

0.5-250 ng/mL

Midazolam
1-hydroxymidazolam

Human

Plasma

LC/MS

EDTA

0.1 mL

0.5-100 ng/mL

Yes

Mifepristone

Human

Plasma

LC/MS

Heparin

0.05 mL

10-2,000 ng/mL

Yes

Mifepristone

Human

Plasma

LC/MS

EDTA or Heparin

0.05 mL

100 - 10,000 ng/mL

Yes

Minocycline

Human

Plasma

LC/MS

Heparin

0.05 mL

10.0 - 4,000 ng/mL

Yes

Minocycline

Human

Plasma

LC/MS

Heparin

0.05 mL

10.0 - 4,000 ng/mL

Yes

Mitiglinide

Human

Plasma

LC/MS

Heparin

0.1 mL

1-1,000 ng/mL

Mitomycin

Human

Plasma

LC/MS

EDTA

0.05 mL

10-5,000 ng/mL

Morphine
Morphine-6-ß-D-glucuronide

Human

Plasma

LC/MS

Heparin

0.1 mL

0.5-500 ng/mL

Yes

Moxifloxacin

Human

Plasma

LC/MS

EDTA

0.025 mL

10.0 - 5,000 ng/mL

Yes

Nabilone

Human

Plasma

LC/MS

Heparin

0.5 mL

100-20,000 pg/mL

N-acetylcysteine

Dog

Plasma

LC/MS

EDTA

0.025 mL

1-1,000 µg/mL

Yes

N-acetylcysteine

Rabbit

Plasma

LC/MS

EDTA

0.025 mL

1-1,000 µg/mL

Yes

Nalbuphine

Human

Plasma

LC/MS

Heparin

0.25 mL

0.1-50 ng/mL

Naloxone

Human

Plasma

LC/MS

Heparin

0.25 mL

0.1-50 ng/mL

Naproxen

Human

Plasma

LC/MS

Heparin

0.025 mL

0.100-100 µg/mL

Yes

Nifuratel

Human

Plasma

LC/MS

Heparin

0.1 mL

1.00 - 200 ng/mL

Nintedanib

Human

Plasma

LC/MS

EDTA

0.05 mL

0.0500 - 50.0 ng/mL

Yes

Nitedanib Carboxylic aicd

Human

Plasma

LC/MS

EDTA

0.05 mL

0.0500 - 50.0 ng/mL

Yes

Norethindrone

Human

Plasma

LC/MS

Heparin

0.25 mL

20-10,000 pg/mL

Yes

Norflaxacin

Human

Plasma

LC/MS

EDTA

0.1 mL

10.0 - 1,000 ng/mL

Yes

Norgestrel
17-deacetylnorgestimate

Human

Plasma

LC/MS

Heparin

0.25 mL

40-20,000 pg/mL
20-10,000 pg/mL

Yes

Omeprazole

Human

Plasma

LC/MS

EDTA

0.05 mL

1.00 - 1,000 ng/mL

Yes

Omeprazole sulfone

Human

Plasma

LC/MS

EDTA

0.05 mL

0.500 - 500 ng/mL

Yes

Ondansetron

Human

Plasma

LC/MS

Heparin

0.05 mL

0.5-250 ng/mL

Yes

Oxybutynin

Human

Plasma

LC/MS

Heparin

0.4 mL

0.0500 - 25.0 ng/mL

Yes

Oxycodone

Human

Plasma

LC/MS

EDTA or Heparin

0.1 mL

0.2-50 ng/mL

Yes

Oxycodone
Oxymorphone
Noroxycodone

Human

Plasma

LC/MS

Heparin

0.5 mL

0.05-25 ng/mL

Yes

Oxypurinol

Human

Serum

LC/MS

N/A

0.025 mL

0.100 - 20.0 ug/mL

Yes

Paclitaxel

Human

Plasma

LC/MS

EDTA or Heparin

0.1 mL

0.5-200 ng/mL

Pioglitazone

Human

Plasma

LC/MS

EDTA

0.05 mL

1.00 - 1,000 ng/mL

Yes

Piperacillin

Human

Plasma

LC/MS

Heparin

0.025 mL

0.0500 - 50.0 ug/mL

Piperacillin

Human

ELF

LC/MS

N/A

0.8 mL

1.00 - 500 ng/mL

Prednisolone

Human

Plasma

LC/MS

Heparin

0.1 mL

1.00 - 1,000 ng/mL

Yes

Prednisone

Human

Plasma

LC/MS

Heparin

0.1 mL

1.00 - 1,000 ng/mL

Yes

Prilocaine

Human

Plasma

LC/MS

EDTA

0.05 mL

0.2-100 ng/mL

Promethazine

Human

Plasma

LC/MS

Heparin

0.1 mL

0.2-100 ng/mL

Quetiapine

Human

Plasma

LC/MS

EDTA or Heparin

0.05 mL

1-1,000 ng/mL

Yes

Repaglinide

Human

Plasma

LC/MS

EDTA

0.05 mL

0.1-100 ng/mL

Yes

Repaglinide

Human

Plasma

LC/MS

EDTA

0.05 mL

0.100 - 100 ng/mL

Yes

Repaglinide

Human

Plasma

LC/MS

Heparin

0.2 mL

0.100 - 100 ng/mL

Yes

Ribavirin

Human

Plasma

LC/MS

Heparin

0.05 mL

5.00 - 2,500 ng/mL

Yes

Riboflavin
Riboflavin 5-phosphate

Dog

Plasma

Fluorescence

Heparin

0.05 mL

20-10,000 ng/mL
40-20,000 ng/mL

Riboflavin
Riboflavin 5-phosphate

Rat

Plasma

Fluorescence

Heparin

0.05 mL

20-10,000 ng/mL
40-20,000 ng/mL

Rifampin
25-desacetylrifampin

Human

Plasma

LC/MS

EDTA

0.05 mL

0.1-20 µg/mL

Yes

Rifaximin

Human

Plasma

LC/MS

Heparin

0.05 mL

0.100 - 25.0 ng/mL

Yes

Rifaximin

Human

Urine

LC/MS

N/A

0.5 mL

0.200 - 100 ng/mL

Yes

Riluzole

Human

Serum

LC/MS

N/A

0.1 mL

1-500 ng/mL

Risperidone
9- hydroxyrisperidone

Human

Plasma

LC/MS

Heparin

0.05 mL

0.1-100 ng/mL

Yes

Ropivacaine

Human

Plasma

LC/MS

Heparin

0.02 mL

1.00 - 1,000 ng/mL

Yes

Rosuvastatin
n-desmethyl rosuvastatin

Human

Plasma

LC/MS

Heparin

0.1 mL

0.1-50 ng/mL

Yes

Simvastatin
Simvastatin hydroxy acid

Human

Plasma

LC/MS

Heparin

0.25 mL

0.05-50 ng/mL

Yes

Sitagliptin

Human

Plasma

LC/MS

Heparin

0.2 mL

0.500 - 1,000 ng/mL

Yes

Sorafenib

Human

Plasma

LC/MS

EDTA

0.05 mL

10-10,000 ng/mL

Yes

Sumatriptan

Human

Plasma

LC/MS

Heparin

0.1 mL

1-200 ng/mL

Tazobactam

Human

Plasma

LC/MS

Heparin

0.02 mL

0.100 - 60.0 ug/mL

Tazobactam

Human

ELF

LC/MS

N/A

0.02 mL

1.00 - 250 ng/mL

Tazobactam M1

Human

Plasma

LC/MS

Heparin

0.02 mL

0.0500 - 30.0 ug/mL

Tenofovir

Human

Plasma

LC/MS

Heparin

0.1 mL

2.00 - 1,000 ng/mL

Yes

Tolbutamide

Human

Plasma

LC/MS

EDTA

0.1 mL

0.1-20 µg/mL

Tolbutamide

Human

Plasma

LC/MS

EDTA

0.02 mL

100 - 50,000 ng/mL

Yes

Tolbutamide
4-hydroxytolbutamide

Human

Urine

LC/MS

N/A

0.1 mL

0.1-20 µg/mL

Trazodone

Human

Plasma

LC/MS

Heparin

0.05 mL

0.2-200 ng/mL

Yes

Tretinoin

Human

Plasma

LC/MS

EDTA

0.2 mL

0.4-10 ng/mL

Yes

Trimetazidine

Human

Plasma

LC/MS

Heparin

0.2 mL

0.200 - 100 ng/mL

Yes

Urea

Human

Plasma

Colorimetric

EDTA

0.01 mL

2.50 - 50.0 mg/dL

N/A

Urea

Human

ELF

Colorimetric

N/A

0.3 mL

0.0500 - 1.00 mg/dL

N/A

Valerenic acid
Hydroxyvalerenic acid
Acetoxyvalerenic acid

Human

Plasma

LC/MS

Heparin

0.2 mL

1-500 ng/mL

Vancomycin

Human

Plasma

LC/MS

Heparin

0.02 mL

50-25,000 ng/mL

Vidagliptin

Human

Plasma

LC/MS

Heparin

0.2 mL

0.500 - 500 ng/mL

Yes

Voruciclib

Human

Plasma

LC/MS

EDTA

0.1 mL

5.00 - 2,000 ng/mL

Yes

Warfarin (R-)

Human

Plasma

LC/MS

Heparin

0.025 mL

2-2,000 ng/mL

Yes

Warfarin (S-)

Human

Plasma

LC/MS

Heparin

0.025 mL

2-2,000 ng/mL

Yes

Yohimbine

Human

Plasma

LC/MS

EDTA

0.1 mL

0.1-50 ng/mL

Zolpidem

Human

Plasma

LC/MS

EDTA

0.05 mL

1-150 ng/mL

Yes

Zolpidem

Baboon

Plasma

LC/MS

EDTA

0.05 mL

1-1,000 ng/mL

Yes

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