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Biomarker: FGF (basic, plasma)

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Analyte:

FGF (basic, plasma)

Platform:

Status:

Validated

Required Sample Volume:

50 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 4.14 pg/mL
ULOQ: 3,716 pg/mL

Biological or Clinical Significance:

One of the most important functions of fibroblast growth factor-2 (FGF-2 or bFGF) is the promotion of endothelial cell proliferation and the physical organization of endothelial cells into tube-like structures, thus promoting angiogenesis. FGF-2 is a more potent angiogenic factor than VEGF or PDGF (platelet-derived growth factor); however, it is less potent than FGF-1. FGF2 has been used to induce artificial gyrification of the mouse brain. Adult neurogenesis within the hippocampus e.g. depends greatly on FGF2.

References:

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