Roche Cobas Analyzer

For Fully Automated, Clinical Chemistry and Electrochemiluminescence (ECL)-Based Immunoassays

Designed for both quantitative and qualitative in vitro assay determinations, the Roche CobasĀ® e 411 analyzer enables BioAgilytix to support immunoassay analysis for a broad range of applications, from biomarker work to infectious disease testing. The analyzerā€™s ECL technology is highly sensitive, yielding reliable, reproducible results for heterogeneous immunoassays. BioAgilytix also uses the Roche CobasĀ® c 311 analyzer for clinical chemistry testing.  

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Ideal Roche Cobas applications:

For reliable, high-throughput results for urgent samplesĀ Ā 

BioAgilytixā€™s scientists utilize the Cobas e 411 analyzer for immunological analysis of serum or plasma. The platform can support the entire menu of 100+ ElecsysĀ® assays, including those for: 

  • Cardiac, bone, and tumor markers 
  • Anemia 
  • Coagulation 
  • Endocrinology 
  • Fertility 
  • Hepatology 
  • Inflammation 
  • Infectious diseases.  

In addition, we support the FDA Emergency Authorized Use (EUA)-approved Elecsys Anti-SARS-CoV-2 immunoassay for the qualitative detection of antibodies to SARS-CoV-2. BioAgilytix utilizes the Cobas c 311 analyzer to support testing from a broad menu of clinical chemistry applications and IVD support.  

The Cobas e 411 analyzerā€™s fully automated intelligent sample workflow supports high throughout, with the ability to run up to 18 assays at a rate of up to 86 tests per hour, or up to 300-450 tests per hour for the c 311 analyzer. Both systems feature STAT sample positions to allow for immediate emergency testing when needed. 

cobas roche analyzer

How the Roche Cobas analyzer works  

The Roche e 411 Cobas analyzer employs ECL technology to detect extremely low levels of antigen, yielding high sensitivity and the ability to detect subtle changes in antigen levels. The Roche c 311 Cobas analyzer performs photometric assays and ion-selective electrode measurements. Innovative tests can therefore be run using lower sample volume, and reagents are protected from external influences to enhance their durability and stability. 

The Cobas also provides a wide measuring range which reduces the need to dilute and repeat samples while minimizing the number of tests that need to be rerun due to out-of-range results.