Explore Our Biomarker Menu


S6RP (pS235/236)

Biological or Clinical Significance:

Ribosomal protein S6 (rpS6) is a component of the 40S ribosomal subunit and is therefore thought to be involved in regulating translation. While the true function of rpS6 is currently under investigation, studies have shown that it is involved in the regulation of cell size, cell proliferation, and glucose homeostasis. Important S6 ribosomal protein phosphorylation sites include several residues (Ser235, Ser236, Ser240, and Ser244) located within a small, carboxy-terminal region of the S6 protein.

S6 Ribosomal Protein (S6RP) is the S6 subunit of the 40S ribosome and it functions to increase translation of mRNA containing a 5′-terminal oligopyramidine tract (5′-TOP). 1 mRNA with a 5’-TOP generally encode proteins involved in the translational machinery, such as proteins involved in ribosome formation. S6RP functions to control translation of proteins which are constituents of the ribosome, and therefore helps to control overall levels of protein translation. The function of S6RP is phosphorylation dependent, and S6RP is phosphorylated by P70S6K in a mitogen dependent fashion.



S6RP (pS235/236)



Experienced Running





Required Sample Volume

Disease State:

MSD Panel:

Speak To A Scientist

    I consent to receive communications (which may include, phone, email, social, and re-targeting ads) from BioAgilytix. I understand I may proactively manage my preferences or opt-out of communications with BioAgilytix at any time using the unsubscribe link provided in all of BioAgilytix’s email communications and can learn more by reading the privacy policy.


    Learn why BioAgilytix is a world-leading authority on immunogenicity studies related to ADA, NAb assay development and validation, isotyping, and more.

    Case Studies

    Learn why we’re a trusted partner to 22 of the top 25 global pharma and biotech companies.