
[EPISODE 25] Adam Stasio Talks, Large Data Sets, Breaking Down Problems, and Tech-Driven Solutions
On this episode of Molecular Moments, Jim McNally, Ph.D., speaks with Adam Stasio, president of SciMed, whose mission is to
(Automated Immunoassays)
(MSD-Multiplex ECLIA)
(SPR Biomarker Interactions)
(ImmunoCAP)
(Western Blot Imager)
(Immune Cell Cytokine Release)
(Low Volume Automated ELISA)
(Multiplex Immunoassay)
SAN DIEGO LAB
~34,000 sq. ft.
CRO
Immunoassay
Mass Spectrometry
USA HQ (DURHAM)
~265,000 sq. ft.
Discovery
Preclinical/clinal
Manufacturing
BOSTON LAB
~22,000 sq. ft.
Bioanalytical Services
Diagnostic Testing
EUROPEAN HQ (HAMBURG)
~2,900 m2 (31,000 sq. ft.)
Assay Development
Validation
Sample Analysis
Global Disease Studies
MELBOURNE LAB
2,777 Square Meters
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Virology
Immunology
FIH trials & early-phase clinical trials
Central laboratory services
BRISBANE LAB
1,566 Square Meters
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Virology
Immunology
FIH trials & early-phase clinical trials
Central laboratory services
Explore the capabilities of each platform in more detail to learn which option will be best for your unique study. Our team is available for specific guidance on platform selection.
On this episode of Molecular Moments, Jim McNally, Ph.D., speaks with Adam Stasio, president of SciMed, whose mission is to
This is the final blog in our three-part flow cytometry series. Part 1 highlighted the broad application of flow cytometry
In this article, Chief Scientific Officer at BioAgilytix, Jim McNally, Ph.D., explores why bioanalysts should prepare for the impending wave
Once the patent on a previously ground-breaking blockbuster molecule comes to an end, there is an opportunity for biosimilar versions
PCR platforms and Good Manufacturing Practices (GMP) certification further enhance European service offerings HAMBURG, GERMANY and DURHAM, NC, May 8,
BioAgilytix continues to build leadership in Europe. Hamburg, Germany April 3, 2023 – BioAgilytix, a leading global bioanalytical laboratory, today
This is the final blog in our three-part flow cytometry series. Part 1 highlighted the broad application of flow cytometry
As we continue our blog series on flow cytometry, we’ll now dive into how this powerful capability supports multiple types
Analytical testing of therapeutic compounds often requires data at the single-cell level. Flow cytometry is a versatile technology that can
(Automated Immunoassays)
(MSD-Multiplex ECLIA)
(SPR Biomarker Interactions)
(ImmunoCAP)
(Western Blot Imager)
(Immune Cell Cytokine Release)
(Low Volume Automated ELISA)
(Multiplex Immunoassay)
SAN DIEGO LAB
~34,000 sq. ft.
CRO
Immunoassay
Mass Spectrometry
USA HQ (DURHAM)
~265,000 sq. ft.
Discovery
Preclinical/clinal
Manufacturing
BOSTON LAB
~22,000 sq. ft.
Bioanalytical Services
Diagnostic Testing
EUROPEAN HQ (HAMBURG)
~2,900 m2 (31,000 sq. ft.)
Assay Development
Validation
Sample Analysis
Global Disease Studies
MELBOURNE LAB
2,777 Square Meters
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Virology
Immunology
FIH trials & early-phase clinical trials
Central laboratory services
BRISBANE LAB
1,566 Square Meters
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Virology
Immunology
FIH trials & early-phase clinical trials
Central laboratory services
Explore the capabilities of each platform in more detail to learn which option will be best for your unique study. Our team is available for specific guidance on platform selection.
On this episode of Molecular Moments, Jim McNally, Ph.D., speaks with Adam Stasio, president of SciMed, whose mission is to
This is the final blog in our three-part flow cytometry series. Part 1 highlighted the broad application of flow cytometry
In this article, Chief Scientific Officer at BioAgilytix, Jim McNally, Ph.D., explores why bioanalysts should prepare for the impending wave
Once the patent on a previously ground-breaking blockbuster molecule comes to an end, there is an opportunity for biosimilar versions
PCR platforms and Good Manufacturing Practices (GMP) certification further enhance European service offerings HAMBURG, GERMANY and DURHAM, NC, May 8,
BioAgilytix continues to build leadership in Europe. Hamburg, Germany April 3, 2023 – BioAgilytix, a leading global bioanalytical laboratory, today
This is the final blog in our three-part flow cytometry series. Part 1 highlighted the broad application of flow cytometry
As we continue our blog series on flow cytometry, we’ll now dive into how this powerful capability supports multiple types
Analytical testing of therapeutic compounds often requires data at the single-cell level. Flow cytometry is a versatile technology that can
The Biacore platform monitors molecular interactions in real time by using a non-invasive label-free technology. This technology reacts to changes in the concentration of molecules at the sensor surface as molecules bind to or detach from the surface.
Biacore’s detection principle is based on surface plasmon resonance (SPR) that is sensitive to changes in refractive index within about 150 nm from the sensor surface. To study the interaction between two binding partners, one partner is attached to the surface and the other is passed over the surface in a continuous flow of sample solution. The SPR response is directly proportional to the change in mass concentration close to the surface.
Biacore is used by BioAgilytix in immunogenicity studies to analyze and characterize anti-drug antibodies (ADAs) and molecular interactions related kinetics, specificity, and concentration. It is also leveraged in the monitoring and characterization of ADAs in pre-clinical and clinical assay development, as well as for isotyping.
The SPR (surface plasmon resonance) on a Biacore is used for the characterization of ADAs and the measurement of therapeutic monoclonal antibodies to Fc-gamma receptors. In addition, membrane proteins such as the interaction of G protein-coupled receptors (GPCRs) with their ligands can be studied with Biacore.
A key advantage of the Biacore platform is its exceptional specificity, which enables label-free interaction analysis to be performed with precision and confidence. Investigations that are characterized by extreme kinetics, interacting partners with low molecular weights, or physiological concentrations that would otherwise be considered beyond the limits of detection can be done using Biacore.
Because of its specificity, this system enables interaction analysis with greater precision in understanding molecular mechanisms and structure-function relationships. In fact, The Biacore T200 offers the highest specificity of any current Biacore system, yielding exceptional data quality with increased precision of measurements that can reveal even minute differences in kinetics.
Learn why the European Immunogenicity Platform (EIP) believes that a multidisciplinary approach is warranted to better understand and minimize drug immunogenicity.
From defining potential drug targets and diagnostic markers to detecting and characterizing ADAs in immunogenicity studies the BioAgilytix team has extensive first-hand experience using Biacore to perform efficient, cost-effective, high-precision bioanalysis.
We will tailor the way we perform immunogenicity and ADA analysis with Biacore based on both the unique specificity and regulatory requirements of your project.