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Biomarker:

NGF-β (plasma)

Biological or Clinical Significance:

Beta-NGF (nerve growth factor) is a secreted dimeric neurotrophin that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. It can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. Beta-NGF additionally promotes mast cell and basophil proliferation and activation and induces the differentiation of B cells.

References:

Analyte:

NGF-β (plasma)

Matrix:

Human K2 EDTA Plasma

Status:

Experienced Running

Sensitivity-LLOQ:

36.7 pg/mL

Sensitivity-ULOQ:

23,700 pg/mL

platform

Luminex, MSD-ECL

Required Sample Volume

50 µL/well

Disease State:

MSD Panel:

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