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Biomarker: NGF-β (plasma)

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Analyte:

NGF-β (plasma)

Platform:

Matrix:

Human K2 EDTA Plasma

Status:

Experienced Running

Required Sample Volume:

50 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 36.7 pg/mL
ULOQ: 23,700 pg/mL

Biological or Clinical Significance:

Beta-NGF (nerve growth factor) is a secreted dimeric neurotrophin that plays a critical role in the development of sympathetic and some sensory neurons in the peripheral nervous system. It can also act in the central nervous system as a trophic factor for basal forebrain cholinergic neurons. Beta-NGF additionally promotes mast cell and basophil proliferation and activation and induces the differentiation of B cells.

References:

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