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Biomarker:

Eotaxin-3 (CCL26) (plasma)

Biological or Clinical Significance:

Chemokine (C-C motif) ligand 26 (CCL26) is a small cytokine belonging to the CC chemokine family that is also called Eotaxin-3, Macrophage inflammatory protein 4-alpha (MIP-4-alpha), Thymic stroma chemokine-1 (TSC-1), and IMAC. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4.[1][2] CCL26 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3.[3] This gene for chemokine is located on human chromosome 7.

References:

Analyte:

Eotaxin-3 (CCL26) (plasma)

Matrix:

Human K2 EDTA Plasma

Status:

Validated

Sensitivity-LLOQ:

6.6 pg/mL

Sensitivity-ULOQ:

1,0440 pg/mL

platform

MSD-ECL

Required Sample Volume

50 µL/well

Disease State:

MSD Panel:

Chemokine Panel 1 (Human)

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