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Biomarker: ERK-1/2 (pT202/pY204)

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Analyte:

ERK-1/2 (pT202/pY204)

Platform:

Matrix:

Tissue Homogenate

Status:

Experienced Running

Biological or Clinical Significance:

Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4).

References:

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