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Biomarker:

FABP3 (Muscle panel)

Biological or Clinical Significance:

Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene.

FABP3 is known to interact with TNNI3K in the context of interacting with cardiac troponin I. The protein also interacts with, VPS28, KIAA159,NUP62, PLK1, UBC, and Xpo1.In HIV, a synthetic peptide corresponding to the immunosuppressive domain (amino acids 574-592) of HIV-1 gp41 downregulates the expression of fatty acid binding protein 3 (FABP3) in peptide-treated PBMCs.
H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain.

References:

Analyte:

FABP3 (Muscle panel)

Matrix:

Rat Serum

Status:

Experienced Running

Sensitivity-LLOQ:

0.066 ng/mL

Sensitivity-ULOQ:

95.2 ng/mL

platform

MSD-ECL

Required Sample Volume

25 µL/well

Disease State:

Toxicity

MSD Panel:

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