Explore Our Biomarker Menu

Biological or Clinical Significance:

πGST is located in the distal tubules of the human kidney whereas alpha GST (πGST) is confined mainly to the proximal tubules. πGST is released into the urine of normal individuals as confirmed by enzyme immunoassay. Any event which precipitates distal tubular damage may cause increased release of πGST into urine and elevations of urinary GST levels have been shown to be indicative of distal tubule damage in renal transplant rejection, nephrotoxicity, infection, diabetes and chronic renal injury. The release of πGST has been shown to be associated with proximal tubular damage, thus simultaneous measurement of πGST and πGST may allow discrimination between proximal and distal tubular damage.

The Pi GST EIISA is a quantitative enzyme immunoassay. The test procedure is based on the sequential addition of sample, antibody-enzyme conjugate and substrate to Microassay wells coated with anti-πGST IgG. The resultant color intensity is proportional to the amount of πGST. The assay range is 1.25 – 40μg/L.






Experienced Running





Required Sample Volume

Disease State:

MSD Panel:

Speak To A Scientist

    I consent to receive communications (which may include, phone, email, social, and re-targeting ads) from BioAgilytix. I understand I may proactively manage my preferences or opt-out of communications with BioAgilytix at any time using the unsubscribe link provided in all of BioAgilytix’s email communications and can learn more by reading the privacy policy.


    Learn why BioAgilytix is a world-leading authority on immunogenicity studies related to ADA, NAb assay development and validation, isotyping, and more.

    Case Studies

    Learn why we’re a trusted partner to 22 of the top 25 global pharma and biotech companies.