Biomarker Menu
Biomarker Menu

Explore Our Biomarker Menu

Including 400+ Biomarker Offerings for a Range of Disease States

Return to Biomarker Menu

Biomarker: PRAS40 (total)

Search for Biomarkers

Analyte:

PRAS40 (total)

Platform:

Status:

Experienced Running

Biological or Clinical Significance:

The proline-rich Akt substrate of 40 kDa (PRAS40) acts at the intersection of the Akt- and mammalian target of rapamycin (mTOR)-mediated signaling pathways.PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase. PRAS40 has been shown to regulate the activity of mammalian target of rapamycin complex 1 (mTORC1), which is a signaling hub connecting insulin signaling and autophagic signaling pathway. PRAS40 has received increasing attention as a potential therapeutic target for the treatment of insulin resistance as it has been demonstrated to reduce systemic hyperglycemia and ameliorate insulin sensitivity of obese mice.

References:

Speak to a Scientist












    What would you like to discuss?

    With whom will we be speaking?






    I consent to receive communications (which may include, phone, email, social, and re-targeting ads) from BioAgilytix. I understand I may proactively manage my preferences or opt-out of communications with BioAgilytix at any time using the unsubscribe link provided in all of BioAgilytix’s email communications and can learn more by reading the privacy policy.

    Yes I confirm that I am over the age of 16 and I consent to communications from BioAgilytix.









    biomarker services

    Services

    See how our premier bioanalytical services support all phases of biomarker, immunogenicity, PK, and cell-based assay studies.

    Explore our services

    case studies

    Case Studies

    Learn why we’re a trusted partner to 22 of the top 25 global pharma and biotech companies.

    Read our case studies