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Biological or Clinical Significance:

This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity.

References:

  • “SLPI.” (n.d.): n. pag. The Human Protein Atlas. Web.  

Analyte:

SLPI

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ:

76.0 pg/mL

Sensitivity-ULOQ:

platform

Ella

Required Sample Volume

Disease State:

MSD Panel:

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