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Biomarker: Stat5 (Tyr694)

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Analyte:

Stat5 (Tyr694)

Platform:

Matrix:

PBMC

Status:

Experienced Running

Biological or Clinical Significance:

STAT5 carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.

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References:

  • “STAT5.” (n.d.): n. pag. The Human Protein Atlas. Web.  

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