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Biomarker: Thrombospondin-1 (THBS1)

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Analyte:

Thrombospondin-1 (THBS1)

Platform:

Matrix:

Human Serum

Status:

Experienced Running

Sensitivity-LLOQ/ULOQ:

LLOQ: 498 pg/mL

Biological or Clinical Significance:

The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.

References:

  • “THBS1.” (n.d.): n. pag. The Human Protein Atlas. Web.  

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