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Biomarker: Troponin I (cTnI-Muscle panel)

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Analyte:

Troponin I (cTnI-Muscle panel)

Platform:

Matrix:

Rat Serum

Status:

Experienced Running

Required Sample Volume:

25 µL/well

Sensitivity-LLOQ/ULOQ:

LLOQ: 0.016 ng/mL
ULOQ: 23.4 ng/mL

Biological or Clinical Significance:

Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I

References:

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