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Biomarker:

Troponin I (cTnI-Muscle panel)

Biological or Clinical Significance:

Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it, myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I

References:

Analyte:

Troponin I (cTnI-Muscle panel)

Matrix:

Rat Serum

Status:

Experienced Running

Sensitivity-LLOQ:

0.016 ng/mL

Sensitivity-ULOQ:

23.4 ng/mL

platform

MSD-ECL

Required Sample Volume

25 µL/well

Disease State:

MSD Panel:

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