ADCC and CDC Assay: Validation and Optimization
Antibody dependent cellular cytotoxicity (ADCC) is a mechanism in host immune defense where antibodies bind to an antigen on the surface of a cell, targeting…
Origins of CRISPR: How it Came to Be
Gene editing isn’t a new concept and has been around for decades. In its infancy, gene editing was time-consuming, inaccurate and costly. That all changed…
Plaque Reduction Neutralization Tests (PRNT) and the Development of New Antiviral Drugs
While infectious disease has always been an important area of scientific and medical research, the recent pandemic has brought this discipline more clearly into the…
What Parameters Are Acquired from a PK Study?
The term “Pharmacokinetics” is derived from “pharmakon” and “kinetikos” in ancient Greek, meaning “drug” and “position in motion,” respectively. It is one of the principal…
The Use of Cell-Based Assays for Translational Medicine Studies
Cell-based assays are an important tool in drug development. One of the biggest challenges when developing a drug is mimicking the appropriate physiological setting to predict…
The Broad Array of Vaccine Options for COVID-19
As we pass the two-year anniversary of the start of the coronavirus pandemic, we are reminded of where we started and how far we have…
Validation of qPCR Assays for Gene Therapy
Though the modern world has progressed a lot in terms of medical interventions and biomedicine, there still are a vast number of diseases and disorders…
BioAgilytix Adds Extensive Capabilities with the Acquisition of MicroConstants and 360biolabs®️
BioAgilytix, a leading global contract research organization focused on supporting its pharmaceutical and biotech partners in all stages of drug development, recently acquired MicroConstants and…
Flow Cytometry in Bioanalysis: Application, Utility and Recent Advancements
Flow Cytometry in Drug Development Flow cytometry is a technique that is used to analyze multiple characteristics of single cells. These characteristics include cell size,…
Update on CAR T-Cell Therapies for the Treatment of Cancer
Chimeric Antigen Receptor (CAR) therapies are a type of cell therapy that consists of modifying immune cells to attack various forms of cancerous cells. While…