Total Bioanalytical Support for Antibody−Drug Conjugates (ADCs)
Antibody−drug conjugates (ADCs) typically contain a small molecule toxin (payload) linked to an antibody framework. The intent is to deliver the toxin in a targeted manner based on the specificity of the antibody, minimizing the amount of toxin needed and directing its effects to the proper cell(s). This combination of modalities, both small and large molecule, requires leveraging multiple bioanalytical tools to characterize the pharmacokinetics and immunogenicity of this class of drug. This webinar will provide an overview of the integrated bioanalysis of ADCs focusing on PK and immunogenicity including case studies and a live Q&A session.