Neutralizing Antibody Assay for Accurate Immune Response Evaluation
Assays for the detection of neutralizing antibodies (NAb) provide a greater depth of insight into the safety and efficacy of biologic drug candidates by assessing potential drug inhibition. By binding to the drug, NAbs can inhibit the drug’s pharmacological function via target binding prevention, thus reducing or neutralizing the drug’s clinical effect. Because of this, NAb assessment is an integral part of any large molecule development program.
With a veteran bioanalytical team that worked on some of the first cases of immunogenicity, BioAgilytix is comprised of experienced scientists who are skilled at differentiating NAbs from other anti-drug antibodies (ADAs) and analyzing their potential immune responses via robust assays developed and validated to your regulatory requirements.